In the game Immune Force players experience the power and ingenuity of the body's natural defenses and the variety of microbial dangers it faces.
The game takes place in a human body, where players cooperate to mobilize the immune system, harnessing macrophages, neutrophils, Killer T-cells, vaccines, treatments, antibodies, and bacteriophages, fighting a continuous onslaught of over two dozen types of bacteria, viruses, fungi, parasites, and cancer.
Each of the different microbes and immune defenses act approximately in accordance with current scientific and medical understanding.
Concepts may be complex, but game play is simple enough to be fun for all ages.
Here is video (18 min) on how to play the game. This uses the play-test version, not the commercial version.
NOTE: Immune Force has now been published, and available for purchase at the link below. All images in the game are either public domain, CC license permitting this use, or purchased royalty-free from Shutterstock. Image credits are here.
Here are links to documents and some images for the game.